pentobarbital will minimize the level or impact of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will decrease the level or effect of amlodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
fentanyl intranasal and pentobarbital equally improve sedation. Stay away from or Use Alternate Drug. Restrict use to people for whom alternative therapy selections are inadequate
pentobarbital will lower the level or influence of diltiazem by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will minimize the level or impact of fruquintinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. If coadministration with moderate CYP3A4 inducers is unavoidable, carry on to administer fruquintinib at advised dosage.
pentobarbital will increase toxicity of ifosfamide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. CYP3A4 inducers may perhaps enhance the metabolism of ifosfamide to its Lively alkylating metabolites.
Parenteral alternatives of barbiturates are very alkaline; Serious care really should be taken to avoid perivascular extravasation or intra-arterial injection; extravascular injection could lead to local tissue injury with subsequent necrosis; outcomes of intra-arterial injection may perhaps vary from transient suffering to gangrene of your limb; any complaint of pain inside the limb warrants stopping the injection
pentobarbital will lower the level or result of quinine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unknown.
This drug may possibly boost the metabolism of estradiol when administered concurrently; clients on oral contraceptives have grown to be Expecting when concurrently addressed with antiepileptic here medicines; suggest an alternate contraceptive approach to women using this drug
pentobarbital will decrease the level or effect of ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Strong CYP3A4 inducers may decrease partiaprevir and ritonavir ranges, and thus reduced efficacy of Viekira Pak
Contraindicated (one)pentobarbital will reduce the level or outcome of doravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the extent or impact of alosetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Not known.
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pentobarbital will decrease the extent or result of diazepam buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Robust or moderate CYP3A4 inducers may well boost price of diazepam elimination; therefore, efficacy of diazepam can be lowered.